Two more excellent psychedelic links

They keep coming—we might have to start a digest/newsletter.

At Quillette, The Case for Psychedelics, which has two psychologists making the case for use on many fronts. This endorsement—not a puff piece or a hedged, tired feature about the psychedelic revival—is a big step. Happy to see it run at Quillette, an up-and-coming home for sanity and freethinking.

And at The Scientist, Decoding The Tripping Brain is a well-linked article summarizing the state of researchers’ understanding of how psychedelics fit into our wider understanding of serotonin psychopharmacology, and how their effects are made manifest on the network level.

Most semi-scientific coverage has focused on psychedelics’ molecular level of action, because this is what was established during the first era of psychedelic research. Understanding the role of psychedelics, and serotonergic compounds more generally, in modulating the activity of the default mode network, and its interaction with the salience network, provides a crucial link between the neurotransmitter level and person-level, describable effects.